The San Manuel Band of Mission Indians Biospecimen Laboratory acquires, processes and stores large numbers of high quality and well annotated tumor tissue specimens.  Specimen collection by the Biospecimen Laboratory  helps scientists to understand the biology of cancer and identify new ways to diagnose and develop new treatments for cancer.  The Biospecimen Laboratory is providing Institutional Review Board-approved investigators with access to optimally preserved tissues that are linked to relevant demographic and clinical data.  All samples are identified by control numbers to protect patient confidentiality. 

The Biospecimen Laboratory is collecting, preparing, preserving, storing and distributing malignant, diseased and normal fresh human tissues and bloods according to established protocols from cancer patients.  Departments which are collaborating with biospecimen collections are: surgical oncology, gynecology and obstetrics, orthopedic surgery, medical oncology, thoracic surgery, ENT and urology.  The VA Loma Linda Health Care System is another collection site.  Between 2009-2018, the Biospecimen Laboratory has had a total of 5583 consented participants and has collected more than 28,420 specimens including tumor tissues, adjacent normal tissues, cells, plasma, peritoneal fluids and bone marrows. The Biospecimen Laboratory has developed standard operating procedures to reduce variability around biospecimen collection and storage.  The Biospecimen Laboratory supports and trains fellows in the oncology/hematology fellowship program as part of the program’s research requirement.  It also provides a research facility for scientists who need research space to perform cancer research.

The Biospecimen Laboratory was recently awarded a grant by the Loma Linda University School of Medicine to promote collaborative and translational research (GCAT 2016-2018) which enhances collaborations between clinical and basic scientists. The Biospecimen Laboratory was also awarded two other GCAT awards in 2011.

The Biospecimen Laboratory has supported 15 separate cancer research projects with specimens, which has resulted in more than 18 publications.

The Biospecimen Laboratory occupies approximately 1,200 sqf on  the first floor of the Chan Shun Pavilion.  The Biospecimen Laboratory is a biosafety level 2 (BSL-2) laboratory with five benches, one tissue culture room, one freezer room and one freezer/refrigerator and chemical compounds room.   A sophisticated database (Open Specimen) is utilized by the Biospecimen Laboratory to enter and retrieve data concerning the collection, storage, quality assurance and distribution of biospecimens with the ability to collect high-quality, standards-based data specific to cancer or set of study requirements.  OpenSpecimen interfaces with the surgical pathology clinical database in the department of pathology to provide optimal and accurate pathologic diagnosis.

Researchers

Researchers interested in gaining access to the biospecimen laboratory’s samples should email Dr. Saied Mirshahidi, requesting access.

Visit the Open Specimen website to view the number and types of samples available.

Complete the Biospecimen Laboratory Tissue Request form to request specimen for research studies.

Watch Donating Your Tissue for Research NCI video.

Biospecimen Laboratory Consent